Okay so this build kind of originated off of one of my favorite unique swords Dreadbeak. The idea is to boost base damage with bloodthirst and reserve exactly or slightly above 50% of life for permanent low life. Now you may say, but adrenaline can be abused so easily if you just reserve at 51%, and I'll say 6 auras/buffs with very good aura effect. Instead of creating a gigantic block of text I'll try to note all the advantages with formatting I'm not used to.
Exactly or close to 50% reservation using a herald of purity and a high level vitality. Enlighten 4 allows for a max level vitality and possibly reduced level arrogance. You ALWAYS want to be low life because of Dreadbeak, Lori's Lantern, and Bloodthirst effects.
Utilize free Dread Banner for defenses/impale effect with Inspirational and a free Flesh and Stone for perma blind when close and MASSIVE maim effect for bossing with Replica Perfect Form.
Pride and Petrified Blood will still be reserved with mana at a slightly reduced cost because you will be pathing to Champion of the Cause.
Petrified blood will allow you to survive most potential surprise one shots due to permanent fortify/increased fortify effect from tree and other forms of mitigation such as being in sand stance for Flesh and Stone. You should be able to out regen/leech any of the degen.
Permanent low life means Bloodthirst is giving you a whopping 120 flat added phys and 9% more damage at 6khp effectively making Dreadbeak become a 530+ pdps powerhouse of a weapon.
Dreadbeak gives permanent onslaught on low life and 100% increased damage so zoom zoom away.
Lori's Lantern gives you the effect of enemies hits being unlucky against you. This again is absurdly powerful considering how defensive you will be built already. (Unlucky if you don't know means the damage is rolled twice against you and lowest number is what you take)
Utilize Imbalanced Guard and Wind Dancer for all occasions. Armor is weird how it mitigates damage so imbalanced guard is VERY strong even if you're already sitting at 50% physical damage reduction through armor alone. Wind dancer just because you will have blind aura with flesh and stone and your evasion won't be awful either.
The Nomad is the last piece of the puzzle. It gives up to 90% increased damage, much needed dexterity, some all res which is nice, and most importantly 50% increased flask charges gained. This mod alone will allow you to much more efficiently spam flasks if you so choose while mapping. This is not a budget item at the moment.
The rest of the gear can be crafted or whatever to fill out resistances and hp. The most high budget option is to grab a pair of elevated shaper boots with the avoid ailment mod and a paradoxica with increased phys damage and increased attack speed. Elevated shaper boots will make you 100% ailment immune and a paradoxica adds upwards of 20-30% more damage possibly higher depending on your investment into added flat physical. All in all the prices break down as such:
Replica perfect form 0 links - 10c
Dreadbeak - 15-20c maybe cheaper but I bought mine for 16c.
Lori's lantern - basically free, well rolled maybe 5c?
The nomad - at the moment looks to be about 100c but it may drop significantly or raise significantly I don't know.
Here is a sample of a lv 100 PoB with gems/links: https://pastebin.com/LRZJ6M51
Also spectral helix is used because fat 250% base damage effectiveness but whatever is fine.
Edit: Updated the PoB. More damage, same items/tree. Added sniper's mark.
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