PoE Snakebite, Cold builds

Hey there, weary exile. I hope you're as hyped for league start as i am. I've thought about league starting Poisonous Concoction Pathfinder, and came up with this PoB. I'm wondering what you guys think, and if there's a better angle to approach it. Damage seems to be okay (?) if calculating with the 300% increased damage mastery and an conservative approach of 3 poison hits/"shotgunning". 36k Poison DPS \ 3 \ 3 = 342k DPS 133k Total Damage Per Poison (3.6s duration) \ 3 \ 3 = 1.2m DPS My defenses however, are all