This is the first of two videos comparing lab runner build with dissolution of the flesh (this video) and dance of the offered (next video).
Both of these items are options to remove all energy shield so that auxium belt provides maximum chill effect, which is in turn reversed by winterweave ring for +30% action speed modifier.
Using dissolution of the flesh allows for the use of rare boots with 6% action speed mod, resistances, and damage and is mostly a better option. However, certain trap layouts and golden key rooms are significantly harder because you cannot heal instantly with a life flask.
pob: https://pastebin.com/HrJwXk0B