Just posting this as I haven't seen anyone mention it. Base damage buff and new higher tier quiver mods and base are all huge for doomfletch prism. Haven't properly pob'd it but just in case anyone wants some inspiration for a potential build.

some thoughts for synergy: low life to use bloodthirst (100 flat phys @ 5k hp is huge), using leaderships price for brittle (low base crit so 15% base crit is huge) scorch (30% on all ele res, great for doomfletch as its all elements) and sap. Trinity support is also good

Ascendancies: for low life champion is really nice, you can set up to have a life flask to give you adrenaline and basically have it up permanently, and fortify more than makes up for the low life loss of defence. Otherwise you can go deadeye because softcoreQuick and dirty sketch pob: https://pastebin.com/iXMAK0xs With just 2 pieces of gear (doomfletch itself and perserverance for permanent onslaught) and some source of the alt ailments (secrets of suffering or leaderships price) sitting on 1 mil single target, with 20k evasion+armour just from auras and almost capped spell supression (one piece of gear will cap it). Considering how insanely well doomfletch scales with gear (its basically the paradoxica of bows) this should have some really good potential